| 21. Ronde | 20.02.2021 | FC Milsami | - | Speranţa Nisporeni | 3:0 |  |
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| 22. Ronde | 25.02.2021 | FC Sfîntul Gheorghe | - | FC Milsami | 1:3 |  |
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| 24. Ronde | 07.03.2021 | FC Zimbru | - | FC Milsami | 1:2 | ||||
| 25. Ronde | 12.03.2021 | FC Milsami | - | FC Codru Lozova | 7:2 | ||||
| 26. Ronde | 19.03.2021 | FC Milsami | - | Dinamo-Auto | 2:2 | ||||
| 27. Ronde | 12.04.2021 | FC Floreşti | - | FC Milsami | 2:5 | ||||
| 28. Ronde | 16.04.2021 | CS Petrocub | - | FC Milsami | 1:1 | |
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| 29. Ronde | 24.04.2021 | FC Milsami | - | Dacia Buiucani | 3:0 | ||||
| 30. Ronde | 30.04.2021 | Speranţa Nisporeni | - | FC Milsami | 0:4 | ||||
| 31. Ronde | 08.05.2021 | FC Milsami | - | FC Sfîntul Gheorghe | 2:1 | ||||
| 32. Ronde | 12.05.2021 | FC Sheriff | - | FC Milsami | 6:0 | ||||
| 33. Ronde | 15.05.2021 | FC Milsami | - | FC Zimbru | 2:1 | ||||
| 34. Ronde | 18.05.2021 | FC Codru Lozova | - | FC Milsami | 2:4 | |
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| 35. Ronde | 22.05.2021 | Dinamo-Auto | - | FC Milsami | 2:0 | ||||
| 36. Ronde | 26.05.2021 | FC Milsami | - | FC Floreşti | 3:2 |
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