| 1. Ronde | 17.01.2021 | Progreso | - | Montevideo City Torque | 0:0 | ||||
| 4. Ronde | 02.02.2021 | Progreso | - | Fénix | 0:1 |  |
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| 5. Ronde | 07.02.2021 | CA Cerro | - | Progreso | 2:0 | ||||
| 6. Ronde | 11.02.2021 | Progreso | - | Defensor Sporting | 3:3 | ||||
| 7. Ronde | 15.02.2021 | Danubio | - | Progreso | 0:1 | |
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| 8. Ronde | 18.02.2021 | Progreso | - | Nacional | 0:1 | ||||
| 9. Ronde | 23.02.2021 | Boston River | - | Progreso | 2:3 | ||||
| 10. Ronde | 02.03.2021 | Progreso | - | Deportivo Maldonado | 1:1 | ||||
| 13. Ronde | 21.03.2021 | Montevideo Wanderers | - | Progreso | 3:0 Toeg. | ||||
| 14. Ronde | 25.03.2021 | Progreso | - | Peñarol | 0:2 |
Uruguay