| 1. Ronde | 09.07.2022 | Universidad Catolica | - | Mushuc Runa | 2:1 | ||||
| 3. Ronde | 24.07.2022 | Mushuc Runa | - | Técnico Universitario | 0:0 | ||||
| 4. Ronde | 31.07.2022 | Cumbayá | - | Mushuc Runa | 1:1 |  |
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| 5. Ronde | 08.08.2022 | Barcelona | - | Mushuc Runa | 4:1 | |
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| 6. Ronde | 13.08.2022 | Mushuc Runa | - | Orense SC | 1:1 | ||||
| 8. Ronde | 28.08.2022 | Mushuc Runa | - | Gualaceo SC | 2:0 |  |
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| 9. Ronde | 04.09.2022 | Macará | - | Mushuc Runa | 3:0 |  |
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| 7. Ronde | 25.09.2022 | Delfín SC | - | Mushuc Runa | 0:0 | ||||
| 12. Ronde | 02.10.2022 | Mushuc Runa | - | Emelec | 0:0 |
Ecuador