| 2. Ronde | 17.01.2021 | CS Cartaginés | - | Guadalupe | 2:1 | ||||
| 5. Ronde | 31.01.2021 | Deportivo Saprissa | - | CS Cartaginés | 4:1 | ||||
| 6. Ronde | 04.02.2021 | AD San Carlos | - | CS Cartaginés | 1:1 | ||||
| 7. Ronde | 07.02.2021 | CS Cartaginés | - | CS Herediano | 1:2 | ||||
| 8. Ronde | 14.02.2021 | Sporting FC | - | CS Cartaginés | 3:1 | ||||
| 12. Ronde | 09.03.2021 | Santos de Guápiles | - | CS Cartaginés | 1:0 | ||||
| 13. Ronde | 14.03.2021 | Guadalupe | - | CS Cartaginés | 0:3 |  |
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| 14. Ronde | 20.03.2021 | CS Cartaginés | - | Municipal Pérez Zeledón | 0:0 | ||||
| 15. Ronde | 31.03.2021 | Limón FC | - | CS Cartaginés | 1:1 | ||||
| 16. Ronde | 04.04.2021 | CS Cartaginés | - | Deportivo Saprissa | 0:0 | ||||
| 17. Ronde | 10.04.2021 | CS Cartaginés | - | AD San Carlos | 1:1 |  |
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| 18. Ronde | 18.04.2021 | CS Herediano | - | CS Cartaginés | 1:2 | |
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| 20. Ronde | 25.04.2021 | LD Alajuelense | - | CS Cartaginés | 4:1 | ||||
| 21. Ronde | 01.05.2021 | CS Cartaginés | - | Municipal Grecia | 2:0 |
Costa Rica