| 3. Ronde | 03.10.2021 | CE Carroi | - | FC Santa Coloma | 2:5 | ||||
| 4. Ronde | 17.10.2021 | FC Santa Coloma | - | FC Ordino | 3:2 | ||||
| 5. Ronde | 24.10.2021 | FC Santa Coloma | - | UE Sant Julià | 1:3 | ||||
| 7. Ronde | 07.11.2021 | FC Santa Coloma | - | Atlétic Escaldes | 1:3 | ||||
| 9. Ronde | 28.11.2021 | UE Engordany | - | FC Santa Coloma | 2:4 | ||||
| 10. Ronde | 19.12.2021 | FC Santa Coloma | - | CE Carroi | 3:0 | ||||
| 12. Ronde | 19.01.2022 | UE Sant Julià | - | FC Santa Coloma | 0:0 | ||||
| 8. Ronde | 26.01.2022 | FC Santa Coloma | - | UE Santa Coloma | 3:1 | ||||
| 13. Ronde | 30.01.2022 | FC Santa Coloma | - | Inter Club d'Escaldes | 3:2 |  |
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| 11. Ronde | 02.02.2022 | FC Ordino | - | FC Santa Coloma | 0:0 | ||||
| 14. Ronde | 06.02.2022 | Atlétic Escaldes | - | FC Santa Coloma | 2:1 | ||||
| 16. Ronde | 20.02.2022 | FC Santa Coloma | - | UE Engordany | 1:1 | ||||
| 17. Ronde | 27.02.2022 | CE Carroi | - | FC Santa Coloma | 0:5 | ||||
| 18. Ronde | 06.03.2022 | FC Santa Coloma | - | FC Ordino | 2:1 | ||||
| 19. Ronde | 13.03.2022 | FC Santa Coloma | - | UE Sant Julià | 2:0 | |
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| 20. Ronde | 20.03.2022 | Inter Club d'Escaldes | - | FC Santa Coloma | 1:2 |  |
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| 21. Ronde | 03.04.2022 | FC Santa Coloma | - | Atlétic Escaldes | 1:1 |
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