| 9. Ronde | 08.09.2021 | Santos de Guápiles | - | AD San Carlos | 2:2 | ||||
| 10. Ronde | 13.09.2021 | AD San Carlos | - | Deportivo Saprissa | 1:0 | ||||
| 12. Ronde | 18.09.2021 | LD Alajuelense | - | AD San Carlos | 2:2 | ||||
| 13. Ronde | 26.09.2021 | AD San Carlos | - | Guadalupe | 4:2 |  |
|||
| 14. Ronde | 03.10.2021 | Municipal Pérez Zeledón | - | AD San Carlos | 1:1 | ||||
| 15. Ronde | 13.10.2021 | AD San Carlos | - | CS Cartaginés | 0:1 | ||||
| 16. Ronde | 17.10.2021 | Jicaral | - | AD San Carlos | 0:4 | ||||
| 17. Ronde | 23.10.2021 | AD San Carlos | - | CS Herediano | 0:0 | ||||
| 18. Ronde | 28.10.2021 | AD San Carlos | - | Sporting FC | 3:1 | ||||
| 19. Ronde | 01.11.2021 | AD Guanacasteca | - | AD San Carlos | 0:1 | ||||
| 20. Ronde | 21.11.2021 | AD San Carlos | - | Santos de Guápiles | 2:4 | ||||
| 22. Ronde | 28.11.2021 | AD San Carlos | - | Municipal Grecia | 1:3 |
Costa Rica