| 1. Ronde | 04.04.2021 | Cobreloa | - | Barnechea | 1:2 | ||||
| 16. Ronde | 24.08.2021 | Barnechea | - | Cobreloa | 1:1 | ||||
| 19. Ronde | 05.09.2021 | Deportes Iquique | - | Barnechea | 4:2 | ||||
| 20. Ronde | 16.09.2021 | Barnechea | - | Rangers | 2:3 | ||||
| 21. Ronde | 22.09.2021 | Puerto Montt | - | Barnechea | 1:0 |  |
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| 22. Ronde | 27.09.2021 | Barnechea | - | Deportes Temuco | 2:0 |  |
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| 23. Ronde | 02.10.2021 | CD Magallanes | - | Barnechea | 1:1 | ||||
| 3. Ronde | 07.10.2021 | Fernández Vial | - | Barnechea | 1:1 | ||||
| 24. Ronde | 10.10.2021 | Barnechea | - | Unión San Felipe | 2:4 | ||||
| 27. Ronde | 27.10.2021 | Barnechea | - | San Marcos | 1:1 | ||||
| 28. Ronde | 01.11.2021 | Santa Cruz | - | Barnechea | 2:0 | ||||
| 29. Ronde | 07.11.2021 | Barnechea | - | Deportes Copiapó | 0:2 |
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