| 7. Ronde | 30.08.2021 | Santos Laguna | - | FC Juárez | 2:0 | ||||
| 8. Ronde | 11.09.2021 | FC Juárez | - | Cruz Azul | 2:1 | ||||
| 9. Ronde | 19.09.2021 | Club León | - | FC Juárez | 0:1 | ||||
| 14. Ronde | 22.09.2021 | FC Juárez | - | Atlético San Luis | 1:0 |  |
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| 11. Ronde | 29.09.2021 | Mazatlán FC | - | FC Juárez | 3:1 | ||||
| 12. Ronde | 02.10.2021 | FC Juárez | - | CF Monterrey | 3:1 | |
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| 10. Ronde | 09.10.2021 | FC Juárez | - | Gallos Blancos | 0:0 | ||||
| 13. Ronde | 17.10.2021 | Pumas UNAM | - | FC Juárez | 1:0 | ||||
| 15. Ronde | 25.10.2021 | CF Pachuca | - | FC Juárez | 1:1 | ||||
| 16. Ronde | 30.10.2021 | FC Juárez | - | Puebla FC | 0:2 |
Uruguay