| 1. Ronde | 22.02.2021 | Emelec | - | Deportivo Cuenca | 4:1 |  |
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| 2. Ronde | 28.02.2021 | Aucas | - | Emelec | 2:3 | ||||
| 3. Ronde | 07.03.2021 | Emelec | - | Delfín SC | 1:0 | |
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| 4. Ronde | 12.03.2021 | Macará | - | Emelec | 1:1 | ||||
| 5. Ronde | 22.03.2021 | Emelec | - | 9 de Octubre | 0:1 | ||||
| 6. Ronde | 02.04.2021 | Olmedo | - | Emelec | 2:3 | ||||
| 7. Ronde | 11.04.2021 | Emelec | - | LDU Quito | 1:1 | ||||
| 8. Ronde | 15.04.2021 | Universidad Catolica | - | Emelec | 2:3 | ||||
| 9. Ronde | 19.04.2021 | Emelec | - | Técnico Universitario | 2:0 | ||||
| 10. Ronde | 02.05.2021 | Orense SC | - | Emelec | 2:3 | ||||
| 12. Ronde | 16.05.2021 | Emelec | - | Guayaquil City | 1:0 | |
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| 13. Ronde | 23.05.2021 | Mushuc Runa | - | Emelec | 1:2 | ||||
| 14. Ronde | 31.05.2021 | Emelec | - | Independiente del Valle | 0:0 | |
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| 11. Ronde | 11.07.2021 | Barcelona | - | Emelec | 1:1 | ||||
| 15. Ronde | 18.07.2021 | Manta | - | Emelec | 0:4 |  |
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Ecuador