| 1. Ronde | 22.08.2021 | SC Toulon [A-jun] | - | Montpellier HSC [A-jun] | 2:1 | ||||
| 2. Ronde | 29.08.2021 | Montpellier HSC [A-jun] | - | Olympique Marseille [A-jun] | 2:1 | ||||
| 3. Ronde | 05.09.2021 | AS Cannes [A-jun] | - | Montpellier HSC [A-jun] | 1:1 | ||||
| 4. Ronde | 12.09.2021 | Montpellier HSC [A-jun] | - | OGC Nice [A-jun] | 2:1 | ||||
| 5. Ronde | 19.09.2021 | Toulouse FC [A-jun] | - | Montpellier HSC [A-jun] | 2:0 | ||||
| 6. Ronde | 26.09.2021 | Montpellier HSC [A-jun] | - | FC Istres [A-jun] | 2:0 | ||||
| 7. Ronde | 03.10.2021 | Pieve di Lota [A-jun] | - | Montpellier HSC [A-jun] | 0:2 | ||||
| 8. Ronde | 09.10.2021 | Montpellier HSC [A-jun] | - | AS Monaco [A-jun] | 1:0 | ||||
| 9. Ronde | 17.10.2021 | US Colomiers [A-jun] | - | Montpellier HSC [A-jun] | 1:0 | ||||
| 11. Ronde | 14.11.2021 | Nîmes Olympique [A-jun] | - | Montpellier HSC [A-jun] | 1:3 |  |
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| 12. Ronde | 21.11.2021 | AS Saint-Étienne [A-jun] | - | Montpellier HSC [A-jun] | 0:0 | ||||
| 13. Ronde | 27.11.2021 | Montpellier HSC [A-jun] | - | AS Béziers [A-jun] | 1:0 | ||||
| 14. Ronde | 05.12.2021 | Olympique Marseille [A-jun] | - | Montpellier HSC [A-jun] | 1:2 | ||||
| 16. Ronde | 22.01.2022 | OGC Nice [A-jun] | - | Montpellier HSC [A-jun] | 1:2 |
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