| 1. Ronde | 28.01.2023 | Willem II [U21] | - | SC Cambuur [U21] | 1:5 |  |
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| 2. Ronde | 04.02.2023 | SC Cambuur [U21] | - | sc Heerenveen [U21] | 2:0 | |
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| 12. Ronde | 11.03.2023 | SC Cambuur [U21] | - | Vitesse [U21] | 0:0 | ||||
| 9. Ronde | 18.03.2023 | sc Heerenveen [U21] | - | SC Cambuur [U21] | 1:0 | ||||
| 8. Ronde | 31.03.2023 | SC Cambuur [U21] | - | Willem II [U21] | 3:3 | ||||
| 11. Ronde | 15.04.2023 | Roda JC Kerkrade [U21] | - | SC Cambuur [U21] | 5:0 | ||||
| 13. Ronde | 13.05.2023 | NEC Nijmegen [U21] | - | SC Cambuur [U21] | 1:2 | ||||
| 14. Ronde | 20.05.2023 | SC Cambuur [U21] | - | FC Emmen [U21] | 8:1 | |
België