| 1. Ronde | 19.07.2021 | Deportes Tolima | - | Deportivo Pereira | 1:0 | ||||
| 2. Ronde | 25.07.2021 | Atlético Nacional | - | Deportes Tolima | 1:0 | ||||
| 3. Ronde | 31.07.2021 | Deportes Tolima | - | Alianza Petrolera | 1:1 | ||||
| 4. Ronde | 09.08.2021 | Atlético Junior | - | Deportes Tolima | 0:0 |  |
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| 5. Ronde | 14.08.2021 | Deportes Tolima | - | Deportivo Pasto | 1:0 | |
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| 11. Ronde | 26.09.2021 | Patriotas FC | - | Deportes Tolima | 0:0 |  |
Colombia