| 1. Ronde | 26.01.2025 | Santa Fe | - | Deportivo Pereira | 2:1 |  |
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| 2. Ronde | 01.02.2025 | Santa Fe | - | Deportes Tolima | 0:0 | ||||
| 3. Ronde | 08.02.2025 | Águilas Doradas | - | Santa Fe | 0:0 | |
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| 4. Ronde | 13.02.2025 | Santa Fe | - | Atlético Nacional | 2:2 | ||||
| 7. Ronde | 28.02.2025 | Envigado FC | - | Santa Fe | 1:7 | ||||
| 8. Ronde | 09.03.2025 | Santa Fe | - | Fortaleza FC | 2:0 | |
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| 20. Ronde | 25.05.2025 | Alianza FC | - | Santa Fe | 6:1 |
Colombia