| 1. Ronde | 16.01.2022 | Once Municipal | - | FAS | 1:1 | ||||
| 3. Ronde | 26.01.2022 | Jocoro FC | - | FAS | 2:2 | ||||
| 5. Ronde | 06.02.2022 | FAS | - | Santa Tecla FC | 2:0 |  |
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| 6. Ronde | 09.02.2022 | Municipal Limeño | - | FAS | 1:1 | ||||
| 7. Ronde | 13.02.2022 | FAS | - | Atlético Marte | 3:0 | |
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| 8. Ronde | 20.02.2022 | Isidro Metapán | - | FAS | 1:1 | |
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| 9. Ronde | 23.02.2022 | FAS | - | AD Chalatenango | 1:3 | ||||
| 13. Ronde | 20.03.2022 | CD Águila | - | FAS | 2:0 | ||||
| 17. Ronde | 13.04.2022 | FAS | - | Municipal Limeño | 1:1 | ||||
| 18. Ronde | 17.04.2022 | Atlético Marte | - | FAS | 1:1 | ||||
| 19. Ronde | 24.04.2022 | FAS | - | Isidro Metapán | 4:1 | |
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| 20. Ronde | 28.04.2022 | AD Chalatenango | - | FAS | 3:2 | ||||
| 21. Ronde | 01.05.2022 | FAS | - | Luis Ángel Firpo | 0:1 | ||||
| 22. Ronde | 07.05.2022 | Platense Zacatecoluca | - | FAS | 1:2 |
El Salvador