| 1. Ronde | 22.08.2021 | SC Toulon [A-jun] | - | Montpellier HSC [A-jun] | 2:1 | ||||
| 2. Ronde | 29.08.2021 | Montpellier HSC [A-jun] | - | Olympique Marseille [A-jun] | 2:1 |  |
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| 11. Ronde | 14.11.2021 | Nîmes Olympique [A-jun] | - | Montpellier HSC [A-jun] | 1:3 | ||||
| 12. Ronde | 21.11.2021 | AS Saint-Étienne [A-jun] | - | Montpellier HSC [A-jun] | 0:0 | ||||
| 13. Ronde | 27.11.2021 | Montpellier HSC [A-jun] | - | AS Béziers [A-jun] | 1:0 | |
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| 19. Ronde | 06.03.2022 | Montpellier HSC [A-jun] | - | Pieve di Lota [A-jun] | 9:0 | |
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| 20. Ronde | 13.03.2022 | AS Monaco [A-jun] | - | Montpellier HSC [A-jun] | 4:0 | ||||
| 21. Ronde | 27.03.2022 | Montpellier HSC [A-jun] | - | US Colomiers [A-jun] | 0:0 | ||||
| 22. Ronde | 03.04.2022 | AC Ajaccio [A-jun] | - | Montpellier HSC [A-jun] | 4:1 | ||||
| 23. Ronde | 10.04.2022 | Montpellier HSC [A-jun] | - | Nîmes Olympique [A-jun] | 3:0 | ||||
| 24. Ronde | 17.04.2022 | Montpellier HSC [A-jun] | - | AS Saint-Étienne [A-jun] | 2:4 | |
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| 25. Ronde | 01.05.2022 | AS Béziers [A-jun] | - | Montpellier HSC [A-jun] | 0:1 |
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