| 1. Ronde | 27.10.2021 | Pyramids FC | - | Misr lel-Maqasah SC | 2:1 | ||||
| 2. Ronde | 31.10.2021 | Pharco FC | - | Pyramids FC | 1:2 | ||||
| 3. Ronde | 04.11.2021 | Pyramids FC | - | Ittihad El Iskandary | 3:0 | ||||
| 7. Ronde | 21.12.2021 | Pyramids FC | - | Tala'ea El Gaish SC | 3:0 | ||||
| 6. Ronde | 25.12.2021 | ENPPI | - | Pyramids FC | 1:1 |  |
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| 12. Ronde | 04.03.2022 | Al Mokawloon | - | Pyramids FC | 0:2 | ||||
| 11. Ronde | 06.04.2022 | Pyramids FC | - | Zamalek | 2:3 | ||||
| 13. Ronde | 09.04.2022 | Pyramids FC | - | Ghazl Al Mehalla | 1:0 | ||||
| 16. Ronde | 27.04.2022 | Pyramids FC | - | Ceramica Cleopatra | 0:1 | ||||
| 17. Ronde | 01.05.2022 | El Gouna | - | Pyramids FC | 1:2 | ||||
| 14. Ronde | 06.05.2022 | Smouha Sporting Club | - | Pyramids FC | 0:2 | ||||
| 21. Ronde | 29.05.2022 | Pyramids FC | - | Al Masry Club | 3:1 | ||||
| 22. Ronde | 22.06.2022 | El Sharkia Lel Dokhan | - | Pyramids FC | 0:3 | ||||
| 23. Ronde | 29.06.2022 | Pyramids FC | - | ENPPI | 1:0 |  |
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| 25. Ronde | 16.07.2022 | Pyramids FC | - | Al Ahly SC | 2:0 | |
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| 26. Ronde | 24.07.2022 | Ismaily | - | Pyramids FC | 0:4 | ||||
| 27. Ronde | 27.07.2022 | Pyramids FC | - | National Bank SC | 1:0 | ||||
| 28. Ronde | 01.08.2022 | Zamalek | - | Pyramids FC | 3:0 | ||||
| 32. Ronde | 22.08.2022 | Future FC | - | Pyramids FC | 1:0 |
Burkina Faso
Mali