| 1. Ronde | 25.01.2020 | Once Caldas | - | Santa Fe | 0:0 |  |
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| 2. Ronde | 31.01.2020 | Santa Fe | - | Envigado FC | 1:1 | ||||
| 3. Ronde | 04.02.2020 | Águilas Doradas | - | Santa Fe | 1:0 | ||||
| 4. Ronde | 09.02.2020 | Santa Fe | - | Atlético Junior | 3:1 |  |
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| 5. Ronde | 16.02.2020 | Patriotas FC | - | Santa Fe | 0:2 | ||||
| 6. Ronde | 22.02.2020 | Santa Fe | - | América de Cali | 2:0 | |
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| 7. Ronde | 04.03.2020 | Millonarios | - | Santa Fe | 0:0 | ||||
| 8. Ronde | 09.03.2020 | Santa Fe | - | Atlético Nacional | 2:2 | |
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| 9. Ronde | 19.09.2020 | Deportivo Pereira | - | Santa Fe | 1:2 | ||||
| 10. Ronde | 28.09.2020 | Santa Fe | - | Millonarios | 1:1 | ||||
| 11. Ronde | 03.10.2020 | Cúcuta Deportivo | - | Santa Fe | 2:3 | |
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| 12. Ronde | 06.10.2020 | Santa Fe | - | Alianza Petrolera | 4:1 | ||||
| 13. Ronde | 13.10.2020 | Jaguares de Córdoba | - | Santa Fe | 1:1 | ||||
| 14. Ronde | 15.10.2020 | Santa Fe | - | La Equidad | 1:0 | ||||
| 15. Ronde | 20.10.2020 | Deportivo Cali | - | Santa Fe | 3:2 | |
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| 16. Ronde | 25.10.2020 | Santa Fe | - | Boyacá Chicó | 3:1 | ||||
| 18. Ronde | 06.11.2020 | Santa Fe | - | Independiente Medellín | 3:0 | |
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| 19. Ronde | 11.11.2020 | Santa Fe | - | Deportes Tolima | 1:0 | ||||
| 20. Ronde | 15.11.2020 | Atlético Bucaramanga | - | Santa Fe | 1:2 |
Argentinië