| 2. Ronde | 24.09.2021 | SS Virtus | - | SS Cosmos | 2:0 |  |
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| 3. Ronde | 02.10.2021 | SS Cosmos | - | SP La Fiorita | 0:2 | |
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| 6. Ronde | 24.10.2021 | SS Cosmos | - | SS Murata | 0:2 | ||||
| 7. Ronde | 30.10.2021 | SP Tre Penne | - | SS Cosmos | 2:0 | |
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| 9. Ronde | 21.11.2021 | SS Cosmos | - | SP Tre Fiori | 0:5 | ||||
| 10. Ronde | 28.11.2021 | SS San Giovanni | - | SS Cosmos | 5:1 | ||||
| 11. Ronde | 04.12.2021 | SS Cosmos | - | FC Domagnano | 0:0 | |
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| 12. Ronde | 12.12.2021 | SP Cailungo | - | SS Cosmos | 2:1 | ||||
| 13. Ronde | 18.12.2021 | SS Cosmos | - | AC Juvenes/Dogana | 1:1 |
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