| 1. Ronde | 15.08.2021 | Excelsior Virton | - | KVC Westerlo | 0:2 | ||||
| 2. Ronde | 20.08.2021 | KVC Westerlo | - | RWD Molenbeek | 0:0 | ||||
| 5. Ronde | 19.09.2021 | KVC Westerlo | - | KMSK Deinze | 2:2 | ||||
| 6. Ronde | 26.09.2021 | Royal Excel Mouscron | - | KVC Westerlo | 1:2 |  |
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| 7. Ronde | 01.10.2021 | KVC Westerlo | - | Lommel SK | 2:0 | ||||
| 8. Ronde | 17.10.2021 | RWD Molenbeek | - | KVC Westerlo | 1:2 | ||||
| 9. Ronde | 24.10.2021 | KVC Westerlo | - | Excelsior Virton | 2:0 | ||||
| 10. Ronde | 31.10.2021 | KMSK Deinze | - | KVC Westerlo | 2:1 | ||||
| 15. Ronde | 25.01.2022 | RWD Molenbeek | - | KVC Westerlo | 0:2 | ||||
| 18. Ronde | 30.01.2022 | Waasland-Beveren | - | KVC Westerlo | 2:1 | ||||
| 17. Ronde | 09.02.2022 | KVC Westerlo | - | KMSK Deinze | 0:3 | ||||
| 24. Ronde | 11.03.2022 | Excelsior Virton | - | KVC Westerlo | 1:0 | ||||
| 25. Ronde | 20.03.2022 | KVC Westerlo | - | Lierse Kempenzonen | 2:0 | ||||
| 27. Ronde | 08.04.2022 | Royal Excel Mouscron | - | KVC Westerlo | 2:6 |
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