| 4. Ronde | 03.02.2021 | Liverpool | - | Rentistas | 2:2 |  |
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| 5. Ronde | 06.02.2021 | Fénix | - | Liverpool | 0:2 | ||||
| 6. Ronde | 10.02.2021 | Liverpool | - | Cerro Largo | 3:2 | ||||
| 7. Ronde | 14.02.2021 | CA Cerro | - | Liverpool | 1:1 |  |
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| 8. Ronde | 17.02.2021 | Liverpool | - | Montevideo Wanderers | 2:1 | ||||
| 9. Ronde | 20.02.2021 | Defensor Sporting | - | Liverpool | 0:3 | |
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| 10. Ronde | 26.02.2021 | Liverpool | - | Peñarol | 1:1 | |
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| 11. Ronde | 07.03.2021 | Danubio | - | Liverpool | 0:1 | ||||
| 12. Ronde | 14.03.2021 | Liverpool | - | River Plate | 3:2 | |
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| 14. Ronde | 24.03.2021 | Liverpool | - | Montevideo City Torque | 4:1 | ||||
| 15. Ronde | 29.03.2021 | Boston River | - | Liverpool | 1:0 |
Uruguay