| 3. Ronde | 04.08.2021 | FAS | - | Jocoro FC | 4:1 | ||||
| 2. Ronde | 08.08.2021 | Jocoro FC | - | Once Municipal | 3:4 |  |
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| 4. Ronde | 14.08.2021 | Jocoro FC | - | Isidro Metapán | 1:0 | ||||
| 5. Ronde | 22.08.2021 | Atlético Marte | - | Jocoro FC | 2:1 | ||||
| 10. Ronde | 19.09.2021 | Platense Zacatecoluca | - | Jocoro FC | 1:1 | ||||
| 12. Ronde | 02.10.2021 | Jocoro FC | - | Luis Ángel Firpo | 2:1 | ||||
| 13. Ronde | 17.10.2021 | Once Municipal | - | Jocoro FC | 2:2 | ||||
| 14. Ronde | 20.10.2021 | Jocoro FC | - | FAS | 0:0 |  |
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| 19. Ronde | 14.11.2021 | AD Chalatenango | - | Jocoro FC | 2:0 | ||||
| 22. Ronde | 27.11.2021 | Alianza | - | Jocoro FC | 2:0 |
El Salvador