| 5. Ronde | 10.10.2021 | Sud América | - | Liverpool | 0:1 | ||||
| 9. Ronde | 30.10.2021 | Montevideo Wanderers | - | Liverpool | 1:0 | ||||
| 11. Ronde | 07.11.2021 | Peñarol | - | Liverpool | 1:0 | ||||
| 12. Ronde | 13.11.2021 | Liverpool | - | Montevideo City Torque | 1:3 | ||||
| 13. Ronde | 19.11.2021 | Villa Española | - | Liverpool | 0:3 | ||||
| 14. Ronde | 26.11.2021 | Liverpool | - | Nacional | 2:2 | ||||
| 15. Ronde | 06.12.2021 | Cerrito | - | Liverpool | 2:1 |
Uruguay