| 6. Ronde | 18.09.2021 | FC Porto [A-jun] | - | Gil Vicente [A-jun] | 1:0 | ||||
| 7. Ronde | 25.09.2021 | Vitória Guimarães [A-jun] | - | FC Porto [A-jun] | 0:2 | ||||
| 8. Ronde | 02.10.2021 | FC Porto [A-jun] | - | FC Vizela [A-jun] | 3:0 |  |
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| 9. Ronde | 16.10.2021 | Paços de Ferreira [A-jun] | - | FC Porto [A-jun] | 2:1 | ||||
| 10. Ronde | 23.10.2021 | Leixões SC [A-jun] | - | FC Porto [A-jun] | 1:2 | |
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| 3. Ronde | 27.10.2021 | Rio Ave FC [A-jun] | - | FC Porto [A-jun] | 1:0 | ||||
| 11. Ronde | 30.10.2021 | FC Porto [A-jun] | - | Sporting Braga [A-jun] | 3:0 | ||||
| 12. Ronde | 07.11.2021 | FC Porto [A-jun] | - | CD Feirense [A-jun] | 4:0 | ||||
| 14. Ronde | 13.11.2021 | FC Porto [A-jun] | - | Rio Ave FC [A-jun] | 4:3 | ||||
| 16. Ronde | 04.12.2021 | FC Porto [A-jun] | - | UD Oliveirense [A-jun] | 8:0 | ||||
| 17. Ronde | 12.12.2021 | Gil Vicente [A-jun] | - | FC Porto [A-jun] | 0:6 | |
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| 21. Ronde | 22.01.2022 | FC Porto [A-jun] | - | Leixões SC [A-jun] | 4:1 | |
Kosovo