| 1. Ronde | 26.07.2021 | Botev Vratsa | - | Arda Kardzhali | 0:0 | ||||
| 2. Ronde | 31.07.2021 | Botev Vratsa | - | Levski Sofia | 2:0 | ||||
| 3. Ronde | 06.08.2021 | Tsarsko Selo Sofia | - | Botev Vratsa | 1:2 |  |
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| 4. Ronde | 16.08.2021 | Botev Vratsa | - | Botev Plovdiv | 1:1 | ||||
| 6. Ronde | 28.08.2021 | Botev Vratsa | - | Lokomotiv Plovdiv | 0:0 | ||||
| 7. Ronde | 12.09.2021 | CSKA 1948 Sofia | - | Botev Vratsa | 5:1 | ||||
| 8. Ronde | 19.09.2021 | Botev Vratsa | - | CSKA Sofia | 2:4 | ||||
| 9. Ronde | 26.09.2021 | PFC Ludogorets Razgrad | - | Botev Vratsa | 3:1 | ||||
| 10. Ronde | 02.10.2021 | Botev Vratsa | - | Lokomotiv Sofia | 2:2 | ||||
| 11. Ronde | 15.10.2021 | Pirin Blagoevgrad | - | Botev Vratsa | 3:1 | ||||
| 12. Ronde | 23.10.2021 | Botev Vratsa | - | Cherno More Varna | 0:0 | ||||
| 14. Ronde | 07.11.2021 | Arda Kardzhali | - | Botev Vratsa | 3:2 | ||||
| 15. Ronde | 22.11.2021 | Levski Sofia | - | Botev Vratsa | 0:0 | ||||
| 17. Ronde | 30.11.2021 | Botev Plovdiv | - | Botev Vratsa | 2:1 | ||||
| 18. Ronde | 04.12.2021 | Botev Vratsa | - | PFC Beroe | 1:0 |
Bulgarije