| 1. Ronde | 15.05.2021 | Villa Española | - | Progreso | 0:0 |  |
|||
| 2. Ronde | 23.05.2021 | Progreso | - | Nacional | 1:3 | ||||
| 3. Ronde | 29.05.2021 | Cerrito | - | Progreso | 0:0 | ||||
| 4. Ronde | 04.06.2021 | Progreso | - | Liverpool | 1:3 | ||||
| 5. Ronde | 12.06.2021 | River Plate | - | Progreso | 4:0 | ||||
| 6. Ronde | 19.06.2021 | Progreso | - | Cerro Largo | 0:0 | |
|||
| 7. Ronde | 24.06.2021 | Deportivo Maldonado | - | Progreso | 1:1 | ||||
| 8. Ronde | 29.06.2021 | Sud América | - | Progreso | 2:4 | |
|||
| 9. Ronde | 05.07.2021 | Progreso | - | Plaza Colonia | 1:2 | ||||
| 10. Ronde | 11.07.2021 | Fénix | - | Progreso | 2:1 | ||||
| 11. Ronde | 16.07.2021 | Progreso | - | Boston River | 1:0 | ||||
| 12. Ronde | 31.07.2021 | Montevideo Wanderers | - | Progreso | 2:0 | ||||
| 14. Ronde | 15.08.2021 | Peñarol | - | Progreso | 1:0 |
Uruguay