| 4. Ronde | 12.09.2021 | Nîmes Olympique [A-jun] | - | Toulouse FC [A-jun] | 0:1 | ||||
| 5. Ronde | 19.09.2021 | Toulouse FC [A-jun] | - | Montpellier HSC [A-jun] | 2:0 | ||||
| 7. Ronde | 03.10.2021 | Toulouse FC [A-jun] | - | SC Toulon [A-jun] | 2:0 | ||||
| 8. Ronde | 10.10.2021 | Olympique Marseille [A-jun] | - | Toulouse FC [A-jun] | 0:1 | ||||
| 11. Ronde | 14.11.2021 | Toulouse FC [A-jun] | - | AS Saint-Étienne [A-jun] | 0:1 | ||||
| 17. Ronde | 06.02.2022 | Montpellier HSC [A-jun] | - | Toulouse FC [A-jun] | 2:1 | ||||
| 18. Ronde | 13.02.2022 | Toulouse FC [A-jun] | - | AS Béziers [A-jun] | 3:1 | ||||
| 22. Ronde | 02.04.2022 | Toulouse FC [A-jun] | - | OGC Nice [A-jun] | 5:1 | ||||
| 23. Ronde | 10.04.2022 | AS Saint-Étienne [A-jun] | - | Toulouse FC [A-jun] | 0:0 |
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