| 1. Ronde | 13.01.2022 | Municipal Pérez Zeledón | - | Municipal Grecia | 1:1 |  |
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| 2. Ronde | 15.01.2022 | Municipal Grecia | - | CS Herediano | 1:1 | ||||
| 4. Ronde | 03.02.2022 | AD Guanacasteca | - | Municipal Grecia | 1:0 | |
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| 5. Ronde | 10.02.2022 | Guadalupe | - | Municipal Grecia | 3:1 | |
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| 6. Ronde | 13.02.2022 | Municipal Grecia | - | CS Cartaginés | 2:0 | ||||
| 7. Ronde | 19.02.2022 | Municipal Grecia | - | AD San Carlos | 0:1 | |
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| 8. Ronde | 27.02.2022 | LD Alajuelense | - | Municipal Grecia | 1:0 | ||||
| 9. Ronde | 02.03.2022 | Municipal Grecia | - | Sporting FC | 0:1 | |
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| 19. Ronde | 04.05.2022 | Municipal Grecia | - | LD Alajuelense | 1:1 | ||||
| 20. Ronde | 08.05.2022 | Sporting FC | - | Municipal Grecia | 3:2 | ||||
| 21. Ronde | 12.05.2022 | Santos de Guápiles | - | Municipal Grecia | 2:0 | ||||
| 22. Ronde | 16.05.2022 | Municipal Grecia | - | Deportivo Saprissa | 2:3 |
Costa Rica