| 6. Ronde | 10.02.2022 | AD Chalatenango | - | Once Municipal | 1:0 | ||||
| 8. Ronde | 20.02.2022 | AD Chalatenango | - | Jocoro FC | 1:0 | ||||
| 9. Ronde | 23.02.2022 | FAS | - | AD Chalatenango | 1:3 | ||||
| 10. Ronde | 27.02.2022 | AD Chalatenango | - | Santa Tecla FC | 1:0 | ||||
| 13. Ronde | 20.03.2022 | AD Chalatenango | - | Isidro Metapán | 1:1 | ||||
| 14. Ronde | 25.03.2022 | AD Chalatenango | - | Alianza | 2:0 | ||||
| 15. Ronde | 03.04.2022 | Luis Ángel Firpo | - | AD Chalatenango | 1:2 |  |
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| 16. Ronde | 10.04.2022 | AD Chalatenango | - | Platense Zacatecoluca | 1:2 | ||||
| 17. Ronde | 13.04.2022 | Once Municipal | - | AD Chalatenango | 0:1 | ||||
| 18. Ronde | 17.04.2022 | AD Chalatenango | - | CD Águila | 0:0 | ||||
| 19. Ronde | 24.04.2022 | Jocoro FC | - | AD Chalatenango | 6:5 | |
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| 20. Ronde | 28.04.2022 | AD Chalatenango | - | FAS | 3:2 | |
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| 21. Ronde | 02.05.2022 | Santa Tecla FC | - | AD Chalatenango | 1:0 | ||||
| 22. Ronde | 07.05.2022 | AD Chalatenango | - | Municipal Limeño | 0:0 |
El Salvador