| 4. Ronde | 12.09.2021 | AC Ajaccio [A-jun] | - | FC Istres [A-jun] | 0:1 | ||||
| 5. Ronde | 19.09.2021 | FC Istres [A-jun] | - | Nîmes Olympique [A-jun] | 5:1 | ||||
| 6. Ronde | 26.09.2021 | Montpellier HSC [A-jun] | - | FC Istres [A-jun] | 2:0 | ||||
| 7. Ronde | 03.10.2021 | FC Istres [A-jun] | - | AS Béziers [A-jun] | 1:2 | ||||
| 8. Ronde | 10.10.2021 | SC Toulon [A-jun] | - | FC Istres [A-jun] | 1:0 | ||||
| 11. Ronde | 13.11.2021 | FC Istres [A-jun] | - | OGC Nice [A-jun] | 0:0 | ||||
| 14. Ronde | 05.12.2021 | FC Istres [A-jun] | - | AS Monaco [A-jun] | 0:1 | ||||
| 18. Ronde | 13.02.2022 | FC Istres [A-jun] | - | Montpellier HSC [A-jun] | 1:0 | ||||
| 17. Ronde | 20.02.2022 | Nîmes Olympique [A-jun] | - | FC Istres [A-jun] | 0:2 | ||||
| 19. Ronde | 06.03.2022 | AS Béziers [A-jun] | - | FC Istres [A-jun] | 1:3 | ||||
| 20. Ronde | 20.03.2022 | FC Istres [A-jun] | - | SC Toulon [A-jun] | 0:2 | ||||
| 21. Ronde | 27.03.2022 | Olympique Marseille [A-jun] | - | FC Istres [A-jun] | 1:0 | ||||
| 24. Ronde | 17.04.2022 | FC Istres [A-jun] | - | Toulouse FC [A-jun] | 1:0 | ||||
| 25. Ronde | 01.05.2022 | FC Istres [A-jun] | - | AS Saint-Étienne [A-jun] | 0:1 |
Frankrijk
Guinea