| 1. Ronde | 13.08.2021 | Go Ahead Eagles | - | sc Heerenveen | 0:1 | ||||
| 2. Ronde | 22.08.2021 | Feyenoord | - | Go Ahead Eagles | 2:0 | ||||
| 3. Ronde | 28.08.2021 | Go Ahead Eagles | - | Sparta Rotterdam | 2:0 | ||||
| 10. Ronde | 24.10.2021 | Vitesse | - | Go Ahead Eagles | 1:2 | ||||
| 13. Ronde | 21.11.2021 | Go Ahead Eagles | - | FC Groningen | 0:1 |  |
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| 14. Ronde | 27.11.2021 | Willem II | - | Go Ahead Eagles | 0:1 | ||||
| 15. Ronde | 05.12.2021 | Go Ahead Eagles | - | FC Twente | 1:2 | ||||
| 16. Ronde | 11.12.2021 | FC Utrecht | - | Go Ahead Eagles | 0:0 | ||||
| 17. Ronde | 19.12.2021 | Go Ahead Eagles | - | NEC Nijmegen | 0:2 | ||||
| 19. Ronde | 15.01.2022 | Go Ahead Eagles | - | RKC Waalwijk | 0:2 | ||||
| 21. Ronde | 06.02.2022 | FC Groningen | - | Go Ahead Eagles | 2:1 | ||||
| 26. Ronde | 12.03.2022 | Sparta Rotterdam | - | Go Ahead Eagles | 1:0 | ||||
| 27. Ronde | 19.03.2022 | Go Ahead Eagles | - | SC Cambuur | 3:0 | ||||
| 30. Ronde | 24.04.2022 | Fortuna Sittard | - | Go Ahead Eagles | 1:0 | ||||
| 31. Ronde | 01.05.2022 | Go Ahead Eagles | - | Vitesse | 1:2 | ||||
| 32. Ronde | 08.05.2022 | NEC Nijmegen | - | Go Ahead Eagles | 1:0 | ||||
| 33. Ronde | 11.05.2022 | Go Ahead Eagles | - | Feyenoord | 0:1 | ||||
| 34. Ronde | 15.05.2022 | sc Heerenveen | - | Go Ahead Eagles | 3:1 |  |
Zambia
