| 1. Ronde | 25.08.2010 | Montevideo Wanderers | - | Nacional | 1:1 | ||||
| 3. Ronde | 05.09.2010 | Montevideo Wanderers | - | Tacuarembó | 2:0 | ||||
| 4. Ronde | 19.09.2010 | Defensor Sporting | - | Montevideo Wanderers | 1:2 |  |
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| 2. Ronde | 23.09.2010 | Peñarol | - | Montevideo Wanderers | 2:1 | |
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| 6. Ronde | 02.10.2010 | Racing | - | Montevideo Wanderers | 0:2 |  |
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| 7. Ronde | 10.10.2010 | Montevideo Wanderers | - | Danubio | 1:1 | ||||
| 8. Ronde | 17.10.2010 | El Tanque Sisley | - | Montevideo Wanderers | 1:1 | |
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| 9. Ronde | 23.10.2010 | Montevideo Wanderers | - | Fénix | 2:2 | ||||
| 10. Ronde | 30.10.2010 | Central Español | - | Montevideo Wanderers | 2:1 | ||||
| 11. Ronde | 07.11.2010 | Montevideo Wanderers | - | Bella Vista | 0:2 | ||||
| 12. Ronde | 13.11.2010 | CA Cerro | - | Montevideo Wanderers | 1:1 | ||||
| 13. Ronde | 21.11.2010 | Montevideo Wanderers | - | River Plate | 1:2 | |
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| 14. Ronde | 28.11.2010 | Liverpool | - | Montevideo Wanderers | 0:2 | ||||
| 15. Ronde | 04.12.2010 | Montevideo Wanderers | - | Miramar Misiones | 1:1 |
Uruguay