| 1. Ronde | 13.03.2022 | Olympiakos | - | Aris Saloniki | 2:1 |  |
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| 2. Ronde | 20.03.2022 | Aris Saloniki | - | Panathinaikos | 0:0 | ||||
| 3. Ronde | 03.04.2022 | Aris Saloniki | - | PAS Giannina | 0:0 | ||||
| 4. Ronde | 10.04.2022 | AEK Athene | - | Aris Saloniki | 1:2 | |
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| 5. Ronde | 17.04.2022 | Aris Saloniki | - | PAOK Saloniki | 1:0 | ||||
| 6. Ronde | 01.05.2022 | Panathinaikos | - | Aris Saloniki | 1:0 | ||||
| 7. Ronde | 08.05.2022 | Aris Saloniki | - | Olympiakos | 0:1 | ||||
| 8. Ronde | 11.05.2022 | PAOK Saloniki | - | Aris Saloniki | 0:1 | ||||
| 9. Ronde | 14.05.2022 | Aris Saloniki | - | AEK Athene | 3:2 | |
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| 10. Ronde | 17.05.2022 | PAS Giannina | - | Aris Saloniki | 0:3 |
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