| 8. Ronde | 12.09.2021 | Alianza | - | Atlético Marte | 3:1 | ||||
| 9. Ronde | 15.09.2021 | Atlético Marte | - | Luis Ángel Firpo | 1:3 | ||||
| 10. Ronde | 19.09.2021 | Once Municipal | - | Atlético Marte | 0:0 | ||||
| 11. Ronde | 26.09.2021 | Atlético Marte | - | FAS | 0:1 | ||||
| 12. Ronde | 02.10.2021 | Atlético Marte | - | Isidro Metapán | 2:0 | ||||
| 13. Ronde | 18.10.2021 | AD Chalatenango | - | Atlético Marte | 2:2 |  |
|||
| 14. Ronde | 21.10.2021 | Santa Tecla FC | - | Atlético Marte | 0:0 | ||||
| 15. Ronde | 24.10.2021 | Atlético Marte | - | CD Águila | 1:2 | ||||
| 16. Ronde | 30.10.2021 | Jocoro FC | - | Atlético Marte | 1:1 | ||||
| 17. Ronde | 02.11.2021 | Atlético Marte | - | Municipal Limeño | 2:0 | ||||
| 18. Ronde | 07.11.2021 | Atlético Marte | - | Platense Zacatecoluca | 0:0 | ||||
| 19. Ronde | 13.11.2021 | Atlético Marte | - | Alianza | 2:1 | ||||
| 20. Ronde | 18.11.2021 | Luis Ángel Firpo | - | Atlético Marte | 2:0 | ||||
| 21. Ronde | 21.11.2021 | Atlético Marte | - | Once Municipal | 1:4 |  |
|||
| 22. Ronde | 27.11.2021 | FAS | - | Atlético Marte | 2:2 |
Uruguay