| 4. Ronde | 20.08.2012 | Club Olimpia | - | Libertad | 2:2 |  |
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| 6. Ronde | 29.08.2012 | Sportivo Carapeguá | - | Libertad | 2:0 | ||||
| 7. Ronde | 03.09.2012 | Libertad | - | Club Rubio Ñu | 3:0 | ||||
| 8. Ronde | 16.09.2012 | Cerro Porteño | - | Libertad | 3:3 | ||||
| 9. Ronde | 24.09.2012 | Libertad | - | Independiente CG | 3:0 |  |
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| 10. Ronde | 01.10.2012 | Libertad | - | Cerro de Franco | 3:0 | |
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| 11. Ronde | 07.10.2012 | Sportivo Luqueño | - | Libertad | 0:2 | ||||
| 12. Ronde | 20.10.2012 | Club Nacional | - | Libertad | 1:2 | ||||
| 13. Ronde | 27.10.2012 | Libertad | - | Tacuary | 2:2 | |
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| 14. Ronde | 30.10.2012 | Guaraní | - | Libertad | 0:2 | ||||
| 15. Ronde | 03.11.2012 | Libertad | - | Club Olimpia | 1:1 | |
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| 18. Ronde | 21.11.2012 | Club Rubio Ñu | - | Libertad | 2:7 |  |
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| 19. Ronde | 25.11.2012 | Libertad | - | Cerro Porteño | 1:0 | ||||
| 20. Ronde | 30.11.2012 | Independiente CG | - | Libertad | 0:5 | |
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| 21. Ronde | 07.12.2012 | Cerro de Franco | - | Libertad | 0:1 | ||||
| 22. Ronde | 16.12.2012 | Libertad | - | Sportivo Luqueño | 2:0 |
Uruguay