| 5. Ronde | 01.05.2022 | Alianza Universidad | - | Santos FC | 4:1 | ||||
| 7. Ronde | 15.05.2022 | Unión Comercio | - | Santos FC | 3:1 | ||||
| 10. Ronde | 05.06.2022 | Santos FC | - | Chavelines Juniors | 3:0 | ||||
| 11. Ronde | 11.06.2022 | Pirata | - | Santos FC | 0:1 | ||||
| 12. Ronde | 19.06.2022 | Santos FC | - | Llacuabamba | 2:2 |  |
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| 13. Ronde | 26.06.2022 | Los Chankas | - | Santos FC | 2:0 |
Peru