| 2. Ronde | 15.01.2022 | Municipal Grecia | - | CS Herediano | 1:1 | ||||
| 3. Ronde | 23.01.2022 | Santos de Guápiles | - | CS Herediano | 0:0 | ||||
| 4. Ronde | 05.02.2022 | CS Herediano | - | Deportivo Saprissa | 1:1 | ||||
| 5. Ronde | 11.02.2022 | AD San Carlos | - | CS Herediano | 1:1 | ||||
| 6. Ronde | 15.02.2022 | CS Herediano | - | Sporting FC | 0:1 | ||||
| 9. Ronde | 03.03.2022 | CS Herediano | - | LD Alajuelense | 1:1 | ||||
| 10. Ronde | 06.03.2022 | Guadalupe | - | CS Herediano | 1:1 |  |
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| 11. Ronde | 01.04.2022 | CS Herediano | - | Municipal Pérez Zeledón | 3:2 | ||||
| 12. Ronde | 05.04.2022 | Jicaral | - | CS Herediano | 0:3 |  |
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| 13. Ronde | 10.04.2022 | CS Herediano | - | Municipal Grecia | 3:1 | ||||
| 15. Ronde | 21.04.2022 | Deportivo Saprissa | - | CS Herediano | 0:1 | |
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| 16. Ronde | 24.04.2022 | CS Herediano | - | AD San Carlos | 1:1 | ||||
| 17. Ronde | 28.04.2022 | Sporting FC | - | CS Herediano | 0:2 | |
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| 18. Ronde | 01.05.2022 | CS Herediano | - | CS Cartaginés | 4:1 | |
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| 20. Ronde | 09.05.2022 | LD Alajuelense | - | CS Herediano | 2:1 | ||||
| 22. Ronde | 15.05.2022 | Municipal Pérez Zeledón | - | CS Herediano | 2:3 | |
Costa Rica