| 3. Ronde | 26.01.2022 | Once Municipal | - | Municipal Limeño | 3:2 | ||||
| 8. Ronde | 20.02.2022 | Platense Zacatecoluca | - | Once Municipal | 1:0 |  |
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| 14. Ronde | 25.03.2022 | Municipal Limeño | - | Once Municipal | 0:0 | ||||
| 15. Ronde | 03.04.2022 | Once Municipal | - | Atlético Marte | 1:0 | ||||
| 16. Ronde | 10.04.2022 | Isidro Metapán | - | Once Municipal | 2:2 | ||||
| 18. Ronde | 17.04.2022 | Luis Ángel Firpo | - | Once Municipal | 0:0 |  |
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| 20. Ronde | 29.04.2022 | Alianza | - | Once Municipal | 1:0 | ||||
| 21. Ronde | 01.05.2022 | CD Águila | - | Once Municipal | 0:1 | |
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| 22. Ronde | 07.05.2022 | Once Municipal | - | Jocoro FC | 0:1 | |
El Salvador