| 2. Ronde | 13.08.2021 | Platense | - | Honduras Progreso | 1:1 | ||||
| 3. Ronde | 16.08.2021 | Platense | - | Real España | 0:2 | ||||
| 5. Ronde | 27.08.2021 | Platense | - | Marathón | 3:1 |  |
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| 6. Ronde | 29.08.2021 | Real Sociedad | - | Platense | 1:1 | ||||
| 7. Ronde | 02.09.2021 | Olimpia | - | Platense | 3:0 | ||||
| 9. Ronde | 16.09.2021 | Victoria | - | Platense | 2:0 | |
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| 10. Ronde | 20.09.2021 | Platense | - | Real Sociedad | 2:3 | ||||
| 17. Ronde | 01.11.2021 | Vida | - | Platense | 3:1 |
Honduras