| 1. Ronde | 06.02.2022 | Albion | - | Rentistas | 3:5 | ||||
| 2. Ronde | 13.02.2022 | Liverpool | - | Albion | 4:0 | ||||
| 3. Ronde | 20.02.2022 | Albion | - | Peñarol | 1:1 | ||||
| 5. Ronde | 13.03.2022 | Albion | - | Montevideo Wanderers | 1:1 |  |
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| 6. Ronde | 20.03.2022 | Plaza Colonia | - | Albion | 1:1 | |
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| 7. Ronde | 02.04.2022 | Albion | - | Boston River | 1:2 | ||||
| 9. Ronde | 16.04.2022 | Albion | - | Cerro Largo | 2:1 | ||||
| 10. Ronde | 24.04.2022 | Fénix | - | Albion | 2:1 | ||||
| 11. Ronde | 07.05.2022 | Albion | - | Defensor Sporting | 0:3 |  |
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| 13. Ronde | 21.05.2022 | Nacional | - | Albion | 2:0 | ||||
| 14. Ronde | 27.05.2022 | Albion | - | Danubio | 1:2 | |
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| 15. Ronde | 04.06.2022 | Deportivo Maldonado | - | Albion | 0:0 | |
Uruguay