| 1. Ronde | 18.07.2010 | Club Olimpia | - | Sport Colombia | 3:0 | ||||
| 2. Ronde | 24.07.2010 | Club Rubio Ñu | - | Sport Colombia | 1:0 | ||||
| 3. Ronde | 01.08.2010 | Sport Colombia | - | Libertad | 1:0 | ||||
| 4. Ronde | 07.08.2010 | 3 de Febrero | - | Sport Colombia | 0:3 | ||||
| 5. Ronde | 14.08.2010 | Sport Colombia | - | Guaraní | 1:1 |  |
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| 7. Ronde | 29.08.2010 | Sport Colombia | - | Club Nacional | 1:2 | ||||
| 17. Ronde | 30.10.2010 | Tacuary | - | Sport Colombia | 2:1 |
Paraguay