| 3. Ronde | 04.08.2021 | FAS | - | Jocoro FC | 4:1 | ||||
| 4. Ronde | 15.08.2021 | Municipal Limeño | - | FAS | 0:3 | ||||
| 5. Ronde | 22.08.2021 | FAS | - | Platense Zacatecoluca | 0:1 | ||||
| 6. Ronde | 26.08.2021 | Alianza | - | FAS | 1:0 |  |
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| 7. Ronde | 29.08.2021 | FAS | - | Luis Ángel Firpo | 3:1 | |
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| 8. Ronde | 12.09.2021 | Once Municipal | - | FAS | 1:3 | |
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| 9. Ronde | 16.09.2021 | AD Chalatenango | - | FAS | 1:2 | |
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| 13. Ronde | 18.10.2021 | FAS | - | CD Águila | 0:1 | ||||
| 16. Ronde | 30.10.2021 | Platense Zacatecoluca | - | FAS | 0:0 | |
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| 18. Ronde | 07.11.2021 | Luis Ángel Firpo | - | FAS | 2:0 |
El Salvador