| 1. Ronde | 13.01.2021 | Jicaral | - | AD San Carlos | 1:1 | ||||
| 2. Ronde | 18.01.2021 | AD San Carlos | - | CS Herediano | 2:1 | ||||
| 3. Ronde | 21.01.2021 | AD San Carlos | - | Guadalupe | 1:0 | ||||
| 4. Ronde | 24.01.2021 | LD Alajuelense | - | AD San Carlos | 1:1 | ||||
| 5. Ronde | 31.01.2021 | AD San Carlos | - | Sporting FC | 0:0 | ||||
| 6. Ronde | 04.02.2021 | AD San Carlos | - | CS Cartaginés | 1:1 | ||||
| 7. Ronde | 08.02.2021 | Santos de Guápiles | - | AD San Carlos | 3:1 | ||||
| 8. Ronde | 15.02.2021 | AD San Carlos | - | Municipal Grecia | 1:4 |  |
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| 10. Ronde | 01.03.2021 | AD San Carlos | - | Limón FC | 0:3 | ||||
| 11. Ronde | 04.03.2021 | Deportivo Saprissa | - | AD San Carlos | 1:1 | ||||
| 12. Ronde | 08.03.2021 | AD San Carlos | - | Jicaral | 0:0 | ||||
| 17. Ronde | 10.04.2021 | CS Cartaginés | - | AD San Carlos | 1:1 | ||||
| 18. Ronde | 19.04.2021 | AD San Carlos | - | Santos de Guápiles | 1:0 | ||||
| 19. Ronde | 22.04.2021 | Municipal Grecia | - | AD San Carlos | 2:1 | ||||
| 20. Ronde | 27.04.2021 | AD San Carlos | - | Municipal Pérez Zeledón | 0:1 | ||||
| 21. Ronde | 01.05.2021 | Limón FC | - | AD San Carlos | 0:3 | ||||
| 22. Ronde | 13.05.2021 | AD San Carlos | - | Deportivo Saprissa | 2:0 |
Costa Rica