| 1. Ronde | 17.09.2000 | Ionikos Nikea | - | Athinaikos | 1:0 | ||||
| 2. Ronde | 24.09.2000 | Athinaikos | - | AEK Athene | 0:3 |  |
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| 3. Ronde | 01.10.2000 | Panachaiki GE | - | Athinaikos | 3:1 | ||||
| 4. Ronde | 29.10.2000 | Athinaikos | - | PS Kalamata | 3:2 | ||||
| 5. Ronde | 05.11.2000 | PAS Giannina | - | Athinaikos | 3:1 | |
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| 6. Ronde | 11.11.2000 | Athinaikos | - | Panionios GSS | 2:0 | |
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| 9. Ronde | 04.12.2000 | Athinaikos | - | Paniliakos Pyrgos | 1:1 | ||||
| 10. Ronde | 10.12.2000 | Panathinaikos | - | Athinaikos | 1:0 | ||||
| 11. Ronde | 17.12.2000 | Athinaikos | - | PAOK Saloniki | 3:4 | |
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| 12. Ronde | 03.01.2001 | Skoda Xanthi | - | Athinaikos | 1:0 | |
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| 13. Ronde | 07.01.2001 | Athinaikos | - | Iraklis Saloniki | 2:0 | ||||
| 14. Ronde | 15.01.2001 | Athinaikos | - | Olympiakos | 1:5 | |
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| 17. Ronde | 05.02.2001 | AEK Athene | - | Athinaikos | 2:1 | ||||
| 18. Ronde | 11.02.2001 | Athinaikos | - | Panachaiki GE | 3:1 | ||||
| 19. Ronde | 19.02.2001 | PS Kalamata | - | Athinaikos | 2:2 | ||||
| 21. Ronde | 04.03.2001 | Panionios GSS | - | Athinaikos | 1:0 | ||||
| 22. Ronde | 11.03.2001 | Athinaikos | - | Aris Saloniki | 2:0 | ||||
| 23. Ronde | 18.03.2001 | Athinaikos | - | OFI Heraklion | 2:3 | ||||
| 24. Ronde | 01.04.2001 | Paniliakos Pyrgos | - | Athinaikos | 3:0 | |
Griekenland