| 1. Ronde | 03.09.2022 | Twente/Heracles [U21] | - | NAC Breda [U21] | 6:2 | ||||
| 3. Ronde | 16.09.2022 | Twente/Heracles [U21] | - | Vitesse [U21] | 2:0 |  |
|||
| 4. Ronde | 01.10.2022 | Roda JC Kerkrade [U21] | - | Twente/Heracles [U21] | 0:3 | |
|||
| 5. Ronde | 08.10.2022 | Twente/Heracles [U21] | - | Go Ahead Eagles [U21] | 2:0 |  |
|||
| 7. Ronde | 22.10.2022 | Twente/Heracles [U21] | - | VVV-Venlo [U21] | 2:1 | ||||
| 8. Ronde | 29.10.2022 | NAC Breda [U21] | - | Twente/Heracles [U21] | 0:1 | |
|||
| 9. Ronde | 05.11.2022 | Twente/Heracles [U21] | - | FC Den Bosch [U21] | 1:0 | ||||
| 13. Ronde | 06.12.2022 | Twente/Heracles [U21] | - | NEC Nijmegen [U21] | 2:0 |
Duitsland