| 1. Ronde | 28.08.2021 | SBV Excelsior [U21] | - | Willem II [U21] | 0:1 | ||||
| 3. Ronde | 18.09.2021 | FC Emmen [U21] | - | Willem II [U21] | 3:4 | ||||
| 6. Ronde | 16.10.2021 | Willem II [U21] | - | De Graafschap [U21] | 1:2 | ||||
| 7. Ronde | 22.10.2021 | Vitesse [U21] | - | Willem II [U21] | 1:3 | ||||
| 12. Ronde | 05.02.2022 | Willem II [U21] | - | SBV Excelsior [U21] | 1:2 | ||||
| 13. Ronde | 12.02.2022 | Willem II [U21] | - | FC Emmen [U21] | 1:2 |
Nederland