| 1. Ronde | 01.08.2021 | Alianza | - | Municipal Limeño | 4:1 | ||||
| 2. Ronde | 08.08.2021 | Municipal Limeño | - | Luis Ángel Firpo | 1:1 | ||||
| 3. Ronde | 11.08.2021 | Once Municipal | - | Municipal Limeño | 4:1 | ||||
| 4. Ronde | 15.08.2021 | Municipal Limeño | - | FAS | 0:3 | ||||
| 5. Ronde | 22.08.2021 | Isidro Metapán | - | Municipal Limeño | 1:0 | ||||
| 6. Ronde | 25.08.2021 | Municipal Limeño | - | Atlético Marte | 1:2 | ||||
| 7. Ronde | 29.08.2021 | Santa Tecla FC | - | Municipal Limeño | 1:1 | ||||
| 8. Ronde | 12.09.2021 | Municipal Limeño | - | CD Águila | 1:0 |  |
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| 9. Ronde | 15.09.2021 | Jocoro FC | - | Municipal Limeño | 3:1 | ||||
| 10. Ronde | 19.09.2021 | AD Chalatenango | - | Municipal Limeño | 1:1 | |
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| 14. Ronde | 09.10.2021 | Municipal Limeño | - | Once Municipal | 1:1 | ||||
| 13. Ronde | 17.10.2021 | Luis Ángel Firpo | - | Municipal Limeño | 1:1 | |
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| 15. Ronde | 24.10.2021 | FAS | - | Municipal Limeño | 2:1 | ||||
| 17. Ronde | 02.11.2021 | Atlético Marte | - | Municipal Limeño | 2:0 |
El Salvador