| 1. Ronde | 01.08.2021 | Nueva Concepción | - | Achuapa | 0:0 |  |
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| 2. Ronde | 07.08.2021 | Achuapa | - | Deportivo Malacateco | 0:0 |  |
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| 4. Ronde | 14.08.2021 | Cobán Imperial | - | Achuapa | 2:0 | ||||
| 5. Ronde | 21.08.2021 | Achuapa | - | Antigua GFC | 0:1 | ||||
| 6. Ronde | 25.08.2021 | Deportivo Guastatoya | - | Achuapa | 2:2 | ||||
| 7. Ronde | 29.08.2021 | Achuapa | - | Santa Lucía | 0:2 |
Colombia