| 1. Ronde | 20.08.2017 | Rampla Juniors | - | Defensor Sporting | 2:2 | ||||
| 2. Ronde | 26.08.2017 | CA Cerro | - | Defensor Sporting | 0:3 | ||||
| 3. Ronde | 03.09.2017 | Defensor Sporting | - | Sud América | 3:2 | ||||
| 4. Ronde | 09.09.2017 | Juventud de Las Piedras | - | Defensor Sporting | 0:1 | ||||
| 5. Ronde | 16.09.2017 | Defensor Sporting | - | Danubio | 1:0 | ||||
| 7. Ronde | 14.10.2017 | Defensor Sporting | - | River Plate | 2:1 | ||||
| 8. Ronde | 05.11.2017 | Peñarol | - | Defensor Sporting | 3:1 | ||||
| 9. Ronde | 08.11.2017 | Defensor Sporting | - | Racing | 4:2 | ||||
| 10. Ronde | 12.11.2017 | El Tanque Sisley | - | Defensor Sporting | 0:2 | ||||
| 11. Ronde | 16.11.2017 | Defensor Sporting | - | Liverpool | 2:2 | ||||
| 12. Ronde | 19.11.2017 | Boston River | - | Defensor Sporting | 0:1 | ||||
| 13. Ronde | 23.11.2017 | Defensor Sporting | - | Montevideo Wanderers | 2:1 |  |
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| 15. Ronde | 03.12.2017 | Defensor Sporting | - | Fénix | 0:2 | |
Uruguay