| 1. Ronde | 18.10.2020 | Guaireña FC | - | Libertad | 0:3 | ||||
| 2. Ronde | 26.10.2020 | Libertad | - | Sol de América | 0:2 | ||||
| 3. Ronde | 01.11.2020 | Cerro Porteño | - | Libertad | 1:0 | ||||
| 4. Ronde | 08.11.2020 | Libertad | - | River Plate | 3:1 | ||||
| 7. Ronde | 21.11.2020 | San Lorenzo | - | Libertad | 2:2 | ||||
| 8. Ronde | 29.11.2020 | Libertad | - | 12 de Octubre de Itauguá | 3:0 |  |
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| 9. Ronde | 06.12.2020 | Sportivo Luqueño | - | Libertad | 2:2 | ||||
| 10. Ronde | 12.12.2020 | Libertad | - | Guaraní | 1:1 | ||||
| 11. Ronde | 19.12.2020 | Libertad | - | Club Olimpia | 2:1 |
Uruguay