| 1. Ronde | 14.08.2021 | RWD Molenbeek | - | Royal Excel Mouscron | 3:1 | ||||
| 2. Ronde | 21.08.2021 | Royal Excel Mouscron | - | Lommel SK | 0:1 | ||||
| 6. Ronde | 26.09.2021 | Royal Excel Mouscron | - | KVC Westerlo | 1:2 | ||||
| 8. Ronde | 17.10.2021 | Lommel SK | - | Royal Excel Mouscron | 3:0 | ||||
| 9. Ronde | 22.10.2021 | Royal Excel Mouscron | - | RWD Molenbeek | 1:1 | ||||
| 10. Ronde | 29.10.2021 | Excelsior Virton | - | Royal Excel Mouscron | 0:2 | ||||
| 11. Ronde | 06.11.2021 | Royal Excel Mouscron | - | SK Deinze | 2:0 | ||||
| 15. Ronde | 11.12.2021 | Royal Excel Mouscron | - | Lommel SK | 2:1 | ||||
| 16. Ronde | 18.12.2021 | SK Deinze | - | Royal Excel Mouscron | 2:2 | ||||
| 17. Ronde | 23.01.2022 | Royal Excel Mouscron | - | Lierse Kempenzonen | 0:0 | ||||
| 19. Ronde | 05.02.2022 | Royal Excel Mouscron | - | Waasland-Beveren | 3:0 | ||||
| 20. Ronde | 12.02.2022 | KVC Westerlo | - | Royal Excel Mouscron | 1:0 | ||||
| 21. Ronde | 20.02.2022 | Royal Excel Mouscron | - | Excelsior Virton | 2:1 | ||||
| 22. Ronde | 27.02.2022 | Lommel SK | - | Royal Excel Mouscron | 0:0 | ||||
| 27. Ronde | 08.04.2022 | Royal Excel Mouscron | - | KVC Westerlo | 2:6 | ||||
| 28. Ronde | 17.04.2022 | Waasland-Beveren | - | Royal Excel Mouscron | 2:0 |
Frankrijk